juvenile dermatomyositis without skin lesions
نویسندگان
چکیده
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منابع مشابه
Juvenile dermatomyositis without skin lesions
Introduction An 8-year-old Iranian girl was referred because she had progressive muscle weakness predominantly in lower limbs since about 2 years ago. She was not able to stand from a sitting position without help and had difficulty climbing stairs. She walked slowly and could not run like before. She had no complaint of dysphagia or dysphonia. She was born through a normal vaginal delivery and...
متن کاملDermatomyositis: immunopathologic study of skin lesions.
BACKGROUND The pathogenesis of the inflammatory processes in the skin of dermatomyositis patients remains unclear. The aim of this study was to investigate the patterns of proliferation and apoptosis of epidermal keratinocytes and dermal infiltrating cells in DM patients. MATERIAL AND METHODS Seventeen skin biopsy specimens from patients with dermatomyositis, which fulfilled the diagnostic cr...
متن کاملJuvenile dermatomyositis.
Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...
متن کاملJuvenile dermatomyositis.
The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...
متن کاملJuvenile Dermatomyositis: A Review
Juvenile dermatomyositis is a systemic vasculopathy, affecting mainly the skin and muscle. In the United States, it is seen in more than three per million children per year. It is diagnosed on the basis of the criteria set by Bohan and Peter. The following review describes the characteristic clinical manifestations, the pathophysiology and immunology of the disease. The various treatment modali...
متن کاملJuvenile Dermatomyositis in Pregnancy
Juvenile dermatomyositis has variable clinical presentations both in and outside of pregnancy. A literature review indicated that optimal maternal and fetal outcomes can be anticipated when the pregnancy is undertaken while the disease is in remission. Poorer outcomes are associated with flare-up of the disease in early pregnancy compared with exacerbation in the second or third trimester, when...
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عنوان ژورنال:
iranian journal of neurologyجلد ۱۴، شماره ۳، صفحات ۱۷۱-۱۷۳
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